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  Nicotinic Acetylcholine Receptors and Signaling Pathways Involved in Addiction and Learning
Location: Academic Research Building, Room R5-265
Date and Time: 11/19/2009 4:00:00 PM
Marina Picciotto, Ph.D., Charles B.G. Murphy Professor, Departments of Psychiatry, Pharmacology, Neurobiology, Yale University College of Medicine

Details:  Pharmacology and Therapeutics Seminar. Anyone wishing to arrange time to speak with Dr. Picciotto should contact: Professor Roger Papke at rlpapke@ufl.edu . Dr. Picciotto is currently Charles B.G. Murphy Professor in the Departments of Psychiatry, Pharmacology, and Neurobiology at the Yale University School of Medicine. She joined the Yale faculty in 1995, after having completed a postdoctoral fellowship with Jean-Pierre Changeux in the Laboratory of Molecular Biology at the Institut Pasteur in Paris, France. She earned a Ph.D. in Molecular Neurobiology at The Rockefeller University in New York City in 1992, where she worked in the Laboratory of Molecular and Cellular Neuroscience under Paul Greengard. She received a B.S. degree in biological sciences from Stanford University, Stanford, California, in 1985. She is currently Senior Editor in the Behavioral/Cognitive/Systems section of the Journal of Neuroscience and Handling Editor of the Journal of Nicotine and Tobacco Research and is a past member of the Neurobiology of Motivated Behavior NIH Study Section. In 1999 she received the Human Frontiers Science Foundation 10th Anniversary award, in 2000 she was awarded the Presidential Early Career Award in Science and Engineering by President Clinton and in 2007, she was honored with the Jacob P. Waletzky Memorial Award for Innovative Research in Drug Addiction and Alcoholism by the Society for Neuroscience. The goal of Dr. Picciotto's research team is to understand the role of single molecules in complex behaviors related to addiction, depression, and learning. She and her colleagues use molecular genetic and pharmacological approaches to link the biochemical, cellular, and anatomical levels of investigation to behavior. Of primary interest is the role of nicotinic acetylcholine receptors in brain function and development. Dr. Picciotto’s laboratory also studies the role of galanin, a neuropeptide that protects against the development of addiction, as well as signaling molecules downstream of nicotinic and galanin receptors, such as calcineurin, CaM kinase I, and adducin, which may mediate long-term changes in behavior downstream of these receptors.

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